Translational Neuroscience at UCSF and the Innovative Genomics Institute
 

Mechanisms of neurodegeneration. Transforming care.

The Neuronal Resilience and Vulnerability in Aging (NERVA) Research Lab is led by Dr. Alexander Ehrenberg at the UCSF Fein Memory and Aging Center and the Innovative Genomics Institute. We uncover the mechanisms that underlie neuronal vulnerability and resilience in aging. By combining experimental models, human neuropathology, and genomic approaches, we map the biology of neurodegeneration across systems. We use these insights to develop precision cell and gene therapies.

 
 
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Alexander Ehrenberg, PhD

Dr. Ehrenberg is the principal investigator of NERVA. He is a biomedical scientist focused on neurological and psychiatric disease pathogenesis and therapeutic development. He received his BA and PhD from UC Berkeley with additional research training at the UC San Francisco Edward and Pearl Fein Memory and Aging Center under the joint mentorship of Dr. Lea Grinberg and Dr. Daniela Kaufer. His graduate training included specialization in neuropathology, epidemiology, comparative neurology, molecular genetics, and cell biology. After graduate school, he completed fellowship training in genome editing, neuropathology, and genetics as a junior investigator working under the joint mentorship of Dr. Jennifer Doudna and Dr. Bruce Miller

Now, Dr. Ehrenberg is an investigator jointly appointed to the UCSF Edward and Pearl Fein Memory and Aging Center and Innovative Genomics Institute. In this role, he continues to study the pathophysiology of age-associated neurological and psychiatric disorders with a focus on identifying and developing targets for cell and gene therapies. He is also an affiliate of the UC Berkeley Center for Resilience Studies to support efforts to improve outcomes for stress disorders, including early childhood adversity and post-traumatic stress.

 
 
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